THE BASIC PRINCIPLES OF ALPRAZOLAM

Metabolism Alprazolam is extensively metabolized in humans, mostly by cytochrome P450 3A4 (CYP3A4), to 2 main Energetic metabolites while in the plasma: 4-hydroxyalprazolam and α-hydroxyalprazolam. The plasma circulation levels of the two active metabolites are below four% of the mother or father. The reported relative potencies in benzodiazepine